Jeffrey Schubert serves as a Principal Scientist at Merck, where he leverages his extensive expertise in drug discovery to drive innovative projects in both small molecule and peptide development. With a robust background in organic synthesis and medicinal chemistry, Jeffrey is instrumental in advancing peptide-based...
Jeffrey Schubert serves as a Principal Scientist at Merck, where he leverages his extensive expertise in drug discovery to drive innovative projects in both small molecule and peptide development. With a robust background in organic synthesis and medicinal chemistry, Jeffrey is instrumental in advancing peptide-based and small molecule discovery initiatives. His proficiency in high-throughput experimentation and cheminformatics allows him to efficiently analyze and optimize compounds, ensuring that promising candidates progress through the drug development pipeline.
Currently, Jeffrey is leading key projects that utilize diverse methodologies, including DNA-encoded libraries (DEL), mRNA technology, and phage display to identify and refine potential therapeutic hits. His innovative approach to drug design is complemented by his creation of PipelinePilot-based programs, which have significantly enhanced peptide synthesis and purification workflows. This not only streamlines the process but also increases the overall efficiency of the drug discovery efforts at Merck.
Jeffrey's skill set encompasses a wide range of techniques, including chromatography, LC-MS, NMR, and UV/Vis spectroscopy, which are critical for characterizing and validating compounds. His deep understanding of organic chemistry and drug discovery principles positions him as a key contributor to Merck's mission of delivering transformative therapies. As he continues to push the boundaries of medicinal chemistry, Jeffrey remains committed to fostering collaboration and innovation within his team, ensuring that they remain at the forefront of pharmaceutical research and development.