Jakkam Madanmohan serves as a Senior Scientist at Organix, where he leverages over a decade of expertise in the design and synthesis of innovative guanine-based antibacterial drugs. His extensive academic background, culminating in a PhD in Chemistry with a focus on synthetic studies towards toxoids...
Jakkam Madanmohan serves as a Senior Scientist at Organix, where he leverages over a decade of expertise in the design and synthesis of innovative guanine-based antibacterial drugs. His extensive academic background, culminating in a PhD in Chemistry with a focus on synthetic studies towards toxoids and transition metal-mediated organic transformations, provides a solid foundation for his contributions to drug discovery and development. At Organix, Jakkam is at the forefront of synthetic process development, specializing in the creation of novel lipids, including deutoriated and fluorinated variants, which are essential for advancing medicinal nanoparticle synthesis.
One of his key projects involves the synthesis of fragmented drugs that are integral to human enzymatic processes, utilizing microwave-assisted reactions to enhance efficiency and yield. This innovative approach not only streamlines the synthesis of complex drug intermediates but also aligns with current trends in sustainable chemistry. Jakkam has also pioneered new synthetic procedures for compounds such as 1-Fluoro-2,4,6-trimethylbenzene, showcasing his ability to tackle challenging synthetic problems with precision and creativity.
His skill set encompasses a wide array of techniques, including lipid synthesis, low-temperature crystallization, and advanced characterization methods such as NMR and LCMS. Jakkam's proficiency in assay development and drug delivery systems further underscores his commitment to translating scientific research into viable therapeutic solutions. As he continues to push the boundaries of organic synthesis and drug design at Organix, Jakkam Madanmohan remains a pivotal figure in the quest for novel antibacterial therapies, contributing significantly to the field of medicinal chemistry.
