Dinesh Gawande is a dedicated Neuroscience Research Associate at Rutgers University–New Brunswick, where he focuses on the intricate mechanisms underlying psychiatric illnesses through the lens of receptor function characterization. His current research is particularly groundbreaking, as he investigates the pivotal role of macrophages in the...
Dinesh Gawande is a dedicated Neuroscience Research Associate at Rutgers University–New Brunswick, where he focuses on the intricate mechanisms underlying psychiatric illnesses through the lens of receptor function characterization. His current research is particularly groundbreaking, as he investigates the pivotal role of macrophages in the repair processes of ribbon synapses following noise-induced cochlear synaptopathy. This work not only sheds light on the cellular responses to auditory trauma but also has broader implications for understanding synaptic plasticity in the context of neuropsychiatric disorders.
Dinesh is spearheading two independent projects that delve into the dual roles of macrophages: first, in the repair of ribbon synapses, and second, in the regulation of postsynaptic AMPA receptor plasticity post-synaptopathy. His expertise in cochlear microdissection for immunohistochemistry, including both whole mount and cryosection techniques, allows him to meticulously analyze the cellular interactions and molecular pathways involved in these processes. Additionally, his proficiency in collecting cochlear perilymph and lysates for proteomics studies further enhances the depth of his research, enabling a comprehensive understanding of the biochemical changes occurring in response to cochlear damage.
Dinesh's skill set is extensive, encompassing genotyping, advanced statistical analysis, and the use of animal models for anxiety and depression studies. His experience with stereotaxic cannulation in rodents, cryostat sectioning, and various histological staining techniques positions him as a versatile researcher capable of tackling complex neuroanatomical questions. Furthermore, his knowledge in pharmacokinetics, HPLC, and Western blotting complements his work in neuron electrophysiology, allowing for a multifaceted approach to studying synaptic function and dysfunction. Through his innovative research, Dinesh Gawande is contributing significantly to the field of neuroscience, paving the way for potential therapeutic strategies for psychiatric disorders linked to synaptic impairment.
