As the Senior Director of Safety Assessment at Charles River Laboratories, Chris Papagiannis plays a pivotal role in advancing the safety and efficacy of biopharmaceuticals through comprehensive toxicological evaluations. With a strong foundation in toxicology and extensive experience in the contract research organization (CRO) sector,...
As the Senior Director of Safety Assessment at Charles River Laboratories, Chris Papagiannis plays a pivotal role in advancing the safety and efficacy of biopharmaceuticals through comprehensive toxicological evaluations. With a strong foundation in toxicology and extensive experience in the contract research organization (CRO) sector, Mr. Papagiannis leads a multidisciplinary team at the Mattawan facility, encompassing areas such as general toxicology, developmental and reproductive toxicology, and safety pharmacology. His expertise extends to neurobehavioral sciences and infusion toxicology, where he ensures that innovative therapies are rigorously assessed for safety and efficacy.
Under his leadership, the Safety Assessment teams employ cutting-edge methodologies, including LC-MS and ELISA techniques, to deliver precise and reliable data that informs drug development processes. Mr. Papagiannis is also deeply involved in the assessment of ADME (Absorption, Distribution, Metabolism, and Excretion) and DMPK (Drug Metabolism and Pharmacokinetics), which are crucial for understanding the pharmacological profiles of new compounds. His collaborative approach fosters strong partnerships with scientific and operational teams, enhancing the integration of safety assessments into the broader research and development pipeline.
In addition to his managerial responsibilities, Chris is committed to mentoring the next generation of scientists in the field of toxicology. His passion for advancing knowledge in areas such as cancer research and vaccine development underscores his dedication to improving public health outcomes. Through his strategic leadership and scientific acumen, Chris Papagiannis continues to drive innovation and excellence at Charles River Laboratories, ensuring that safety assessments meet the highest standards in the industry.
