Kurt Morgenstern is a distinguished Principal Scientist at Charles River Laboratories, where he leverages his extensive expertise in proteomic mass spectrometry and analytical biochemistry to drive innovative research and development initiatives. With a solid foundation in workflows involving micro-scale multidimensional fractionations, Kurt specializes in robust...
Kurt Morgenstern is a distinguished Principal Scientist at Charles River Laboratories, where he leverages his extensive expertise in proteomic mass spectrometry and analytical biochemistry to drive innovative research and development initiatives. With a solid foundation in workflows involving micro-scale multidimensional fractionations, Kurt specializes in robust quantitative nanoLC-MS/MS assays that are pivotal for high-throughput screening applications. His current role encompasses the development of cutting-edge mass spectrometry assays, including a novel method for the quantification of C-terminal diethylamide amino acid derivatives in Glatiramer acetate, which has significant implications for therapeutic monitoring and drug development.
Kurt's proficiency extends to the characterization of antibody biosimilars through intact mass analysis and peptide mapping, ensuring accurate sequence confirmation and the identification of critical post-translational modifications (PTMs), N- and O-linked glycosylations, and disulfide bond formations. His bioanalytical approaches for quantifying antibodies in serum are instrumental in advancing the field of biopharmaceuticals, particularly in the context of regulatory compliance and therapeutic efficacy.
Prior to his tenure at Charles River Laboratories, Kurt honed his skills at Blue Stream Laboratories, where he further developed his passion for high-throughput mass spectrometry and enzyme assays. His commitment to excellence in proteomics and quantitative analytics positions him as a leading figure in the life sciences sector, where he continues to contribute to the advancement of biotechnological innovations. With a keen eye for detail and a dedication to scientific rigor, Kurt Morgenstern exemplifies the qualities of a forward-thinking scientist poised to make significant contributions to the evolving landscape of biochemistry and mass spectrometry.
