Huolong Liu currently serves as a Senior Engineer II at Alexion Pharmaceuticals, Inc., where he plays a pivotal role in the commercialization readiness of oral solid dosage (OSD) drug products. With a robust foundation in pharmaceutical manufacturing and a Ph.D. focused on the modeling and...
Huolong Liu currently serves as a Senior Engineer II at Alexion Pharmaceuticals, Inc., where he plays a pivotal role in the commercialization readiness of oral solid dosage (OSD) drug products. With a robust foundation in pharmaceutical manufacturing and a Ph.D. focused on the modeling and control of batch pulsed top-spray fluidized bed granulation, Huolong brings a wealth of expertise to his position. His hands-on experience in experimental studies has equipped him with a deep understanding of process parameters and the intricacies of population balance model (PBM) development, essential for ensuring product quality and compliance with Good Manufacturing Practices (GMP).
In his current role, Huolong leads key projects such as New Drug Application (NDA) submissions and agency query responses, demonstrating his proficiency in navigating the regulatory landscape of the pharmaceutical industry. His leadership in lifecycle management (LCM) projects further underscores his commitment to continuous improvement and innovation in drug product development. Huolong also spearheads drug product modeling and simulation initiatives, leveraging advanced techniques like computational fluid dynamics (CFD) and hybrid statistical-PBM modeling to optimize manufacturing processes.
His skill set extends to nanotechnology and nanomaterials, where he employs tools such as atomic force microscopy (AFM) and high-performance liquid chromatography (HPLC) to enhance product formulation and characterization. Huolong's dedication to quality by design (QbD) principles ensures that every aspect of the drug development process is meticulously planned and executed, ultimately contributing to the successful delivery of safe and effective therapies. His blend of research acumen and practical engineering skills positions him as a key contributor to Alexion's mission of advancing innovative treatments for patients.
